Decrease of the incidence of human and canine visceral leishmaniasis after dog vaccination with Leishmune in Brazilian endemic areas.

@article{PalatnikdeSousa2009DecreaseOT,
  title={Decrease of the incidence of human and canine visceral leishmaniasis after dog vaccination with Leishmune in Brazilian endemic areas.},
  author={Clarisa Beatriz Palatnik-de-Sousa and Ilce Silva-Antunes and Adilson de Aguiar Morgado and Ingrid Menz and Marcos Palatnik and Carlile Lavor},
  journal={Vaccine},
  year={2009},
  volume={27 27},
  pages={
          3505-12
        }
}
Leishmune, the first prophylactic vaccine licensed against canine visceral leishmaniasis (CVL), has been used in Brazil since 2004, where seropositive dogs are sacrificed in order to control human visceral leishmaniasis (VL). We demonstrate here that vaccination with Leishmune does not interfere with the serological control campaign (110,000 dogs). Only 1.3% of positivity (76 among 5860) was detected among Leishmune uninfected vaccinees. We also analyzed the possible additive effect of… Expand
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