Decrease of the atrial fibrillatory rate, increased organization of the atrial rhythm and termination of atrial fibrillation by AZD7009.

@article{AunesJansson2013DecreaseOT,
  title={Decrease of the atrial fibrillatory rate, increased organization of the atrial rhythm and termination of atrial fibrillation by AZD7009.},
  author={Maria Aunes-Jansson and Nils G Edvardsson and Martin Stridh and Leif S{\"o}rnmo and Lars Frison and Anders R Berggren},
  journal={Journal of electrocardiology},
  year={2013},
  volume={46 1},
  pages={29-35}
}
BACKGROUND The atrial fibrillatory rate (AFR), on AZD7009 as compared to placebo, was investigated as a potential biomarker for electrophysiological effect in early antiarrhythmic drug development. METHODS Patients with permanent AF received infusions of AZD7009 and placebo in an exploratory two-way, single-blind, randomized cross-over study. The ECG was continuously recorded, and following QRST cancellation the AFR, its standard deviation (SD), the exponential decay and the atrial… CONTINUE READING
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Characterization of the in vivo and the in vitro electrophysiological effects of the novel antiarrhythmic agent

  • L Carlsson, D Cartier, S. Nattel
  • Journal of Electrocardiology
  • 2013
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