Decrease of hypochlorous acid and hydroxyl radical generated by stimulated human neutrophils: comparison in vitro of some thiol-containing drugs.

Abstract

Among reactive oxygen species generated by human neutrophils during inflammatory disorders, hypochlorous acid and hydroxyl radical are especially involved in many diseases such as arteriosclerosis or emphysema. It was shown in vitro that two thiol-containing drugs, mesna and N-acetylcysteine, have antioxidant properties towards these oxidants. The 50… (More)

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@article{Gressier1994DecreaseOH, title={Decrease of hypochlorous acid and hydroxyl radical generated by stimulated human neutrophils: comparison in vitro of some thiol-containing drugs.}, author={Bernard Gressier and A Cabanis and S ebastien Leb{\`e}gue and Claude Brunet and Thierry Dine and Mathieu Luyckx and Marie C{\'e}cile Cazin and J. C. Cazin}, journal={Methods and findings in experimental and clinical pharmacology}, year={1994}, volume={16 1}, pages={9-13} }