Decrease of hippocampal GABA B receptor-mediated inhibition after hyperthermia-induced seizures in immature rats.

@article{Tsai2006DecreaseOH,
  title={Decrease of hippocampal GABA B receptor-mediated inhibition after hyperthermia-induced seizures in immature rats.},
  author={Min-Lan Tsai and L. Stan Leung},
  journal={Epilepsia},
  year={2006},
  volume={47 2},
  pages={277-87}
}
PURPOSE Whether febrile seizures have detrimental consequences on the brain is still controversial. We hypothesized that neuronal inhibition in the hippocampus is altered after hyperthermia-induced seizures in immature rats. METHODS Rats were given a single seizure by a heat lamp on postnatal day (PND) 15, or repeated seizures by heated air on PND 13 to 15. Fourteen or 30 days after the seizure(s), laminar field potentials were recorded by 16-channel silicon probes in CA1 and the dentate… CONTINUE READING