Decrease of glial fibrillary acidic protein in rat frontal cortex following aluminum treatment.

@article{GuoRoss1999DecreaseOG,
  title={Decrease of glial fibrillary acidic protein in rat frontal cortex following aluminum treatment.},
  author={Shirley X. Guo-Ross and Evelyn Y Yang and Thomas J. Walsh and Stephen C Bondy},
  journal={Journal of neurochemistry},
  year={1999},
  volume={73 4},
  pages={1609-14}
}
Aluminum lactate was injected either intraperitoneally or stereotactically into the lateral cerebral ventricles of rats. Rats were killed at various times after treatment, and frontal cortex, hippocampus, and striatum were dissected out. Microtiter plate-based sandwich ELISA and immunohistochemistry were used to measure the glial fibrillary acidic protein (GFAP) concentration. GFAP levels were significantly decreased in frontal cortex 7 days after a single lateral ventricular injection of… CONTINUE READING

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