Decrease of Thymic Hormone Serum Level in Cockayne Syndrome

@article{Bensman1982DecreaseOT,
  title={Decrease of Thymic Hormone Serum Level in Cockayne Syndrome},
  author={Albert Bensman and Mireille Dardenne and J. -F. Bach and J{\'e}r{\^o}me valleteau De Mouillac and G{\'e}raud Lasfargues},
  journal={Pediatric Research},
  year={1982},
  volume={16},
  pages={92-94}
}
Summary: Previous reports concerning children with Cockayne syndrome had described decreased T cell proliferative responses and renal anomalies which could be associated with immunologic disturbances. Herein, the thymic function was evaluated by measuring the serum level of thymic hormone. This serum level was found to be undetectable or decreased in seven cases of Cockayne syndrome. Active serum concentrations varied between 0 and 1/8, whereas normal children of the same age show activity in… CONTINUE READING

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Speculation : The discrepancy between low levels of thymic hormone found in seven cases of Cockayne syndrome which represents a biologic sign of aging , and normal T cell function , is still unclear : we can suppose that the number of long - lived T cells is sufficient to provide normal T cell responses after decrease of thymic production .
Speculation : The discrepancy between low levels of thymic hormone found in seven cases of Cockayne syndrome which represents a biologic sign of aging , and normal T cell function , is still unclear : we can suppose that the number of long - lived T cells is sufficient to provide normal T cell responses after decrease of thymic production .
Speculation : The discrepancy between low levels of thymic hormone found in seven cases of Cockayne syndrome which represents a biologic sign of aging , and normal T cell function , is still unclear : we can suppose that the number of long - lived T cells is sufficient to provide normal T cell responses after decrease of thymic production .
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