Decrease of B-cells and autoantibodies after low-dose methotrexate.

  • Ingrid B Boehm
  • Published 2003 in
    Biomedicine & pharmacotherapy = Biomedecine…


The purpose was to assess the efficacy of low-dose methotrexate (MTX) on immunological parameters in patients with lupus erythematosus (LE) under short- (</=10 weeks) vs. long-term (>10 weeks) conditions. Patients who did not respond to classical LE treatment (antimalarials and/or glucocorticosteroids) were retrospectively analyzed. Twenty-two LE-patients… (More)


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