Decrease in the numbers of dendritic cells and CD4+ T cells in cerebral perivascular spaces due to natalizumab.

@article{Martin2008DecreaseIT,
  title={Decrease in the numbers of dendritic cells and CD4+ T cells in cerebral perivascular spaces due to natalizumab.},
  author={Maria del Pilar Martin and Petra D. Cravens and Ryan C Winger and Elliot M. Frohman and Michael Karl Racke and Todd N Eagar and Scott S. Zamvil and Martin S. Weber and Bernhard Hemmer and Nitin Karandikar and Betty K Kleinschmidt-Demasters and Olaf St{\"u}ve},
  journal={Archives of neurology},
  year={2008},
  volume={65 12},
  pages={1596-603}
}
OBJECTIVE To extend our studies on the prolonged and differential effect of natalizumab on T lymphocyte numbers in the cerebrospinal fluid, we investigated the number and phenotypes of leukocytes and the expression of major histocompatibility complex (MHC) classes I and II in cerebral perivascular spaces (CPVS). We hypothesized that natalizumab reduces the number of antigen presenting cells in CPVS. DESIGN A case-control study in which inflammatory cell numbers in the CPVS of cerebral tissue… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 9 times over the past 90 days. VIEW TWEETS
51 Citations
30 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 51 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 30 references

Similar Papers

Loading similar papers…