Decrease in the nucleo-cytoplasmic volume ratio of rabbit spinal ganglion neurons with age

  title={Decrease in the nucleo-cytoplasmic volume ratio of rabbit spinal ganglion neurons with age},
  author={M. Ledda and L. Barni and L. Altieri and E. Pannese},
  journal={Neuroscience Letters},
  • M. Ledda, L. Barni, +1 author E. Pannese
  • Published 2000
  • Biology, Medicine
  • Neuroscience Letters
  • Nuclear and perikaryal volumes, as well as the mean percentage of perikaryal volume occupied by lipofuscin, were estimated in spinal ganglion neurons of 12, 42 and 79 month-old rabbits. The volume ratio between nucleus and perikaryal cytoplasm (N/C volume ratio) decreased progressively and significantly with increasing age. This was not a consequence of the perikaryal enlargement due to the age-related lipofuscin accumulation since the same result was obtained when the volume occupied by… CONTINUE READING
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