Decrease in neuron-restrictive silencer factor (NRSF) mRNA levels during differentiation of cultured neuroblastoma cells.

@article{Nishimura1996DecreaseIN,
  title={Decrease in neuron-restrictive silencer factor (NRSF) mRNA levels during differentiation of cultured neuroblastoma cells.},
  author={Eiji Nishimura and Kazuki Sasaki and Kayo Maruyama and Toshihiko Tsukada and Ken Yamaguchi},
  journal={Neuroscience letters},
  year={1996},
  volume={211 2},
  pages={101-4}
}
Non-neuronal cells and undifferentiated neuronal progenitors express the neuron-restrictive silencer factor (NRSF), a silencer protein which represses neuronal gene transcription in these cell types. Neuroblastoma, a childhood tumor of neuroectodermal origin, shares some biological properties with neuronal progenitor cells and can acquire neuronal… CONTINUE READING