Decrease in Salivary Secretion by Radiation Mediated by Nitric Oxide and Prostaglandins

@article{Cal2006DecreaseIS,
  title={Decrease in Salivary Secretion by Radiation Mediated by Nitric Oxide and Prostaglandins},
  author={Carolina de la Cal and Alejandro Lomniczi and Claudia Ester Mohn and Andrea De Laurentiis and Mariana Casal and Ana P. Chiarenza and Dante Agust{\'i}n Paz and Samuel M. Mccann and Val{\'e}ria Rettori and Juan Carlos Elverd{\'i}n},
  journal={Neuroimmunomodulation},
  year={2006},
  volume={13},
  pages={19 - 27}
}
Objective: In the present work, we evaluated the effect of exposing the submandibular glands (SMG) to radiation, studying different functional parameters such as salivary secretion, nitric oxide (NO) production, reactive oxygen species formation, prostaglandin (PGE) content and apoptosis. Methods: We irradiated rats in the head and neck region with a single dose of γ-ray radiation of 15 Gy. Two hours after radiation, we measured norepinephrine-induced salivary secretion. After that, the SMG… CONTINUE READING

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