Decorin regulates assembly of collagen fibrils and acquisition of biomechanical properties during tendon development

@article{Zhang2006DecorinRA,
  title={Decorin regulates assembly of collagen fibrils and acquisition of biomechanical properties during tendon development},
  author={Guiyun Zhang and Yoichi Ezura and Inna Chervoneva and Paul S. Robinson and David P. Beason and Ehren T. Carine and Louis J Soslowsky and Renato V. Iozzo and David E. Birk},
  journal={Journal of Cellular Biochemistry},
  year={2006},
  volume={98}
}
Tendon function involves the development of an organized hierarchy of collagen fibrils. Small leucine‐rich proteoglycans have been implicated in the regulation of fibrillogenesis and decorin is the prototypic member of this family. Decorin‐deficient mice demonstrate altered fibril structure and mechanical function in mature skin and tail tendons. However, the developmental role(s) of decorin needs to be elucidated. To define these role(s) during tendon development, tendons (flexor digitorum… 

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