Decorin regulates assembly of collagen fibrils and acquisition of biomechanical properties during tendon development

@article{Zhang2006DecorinRA,
  title={Decorin regulates assembly of collagen fibrils and acquisition of biomechanical properties during tendon development},
  author={G. Zhang and Y. Ezura and I. Chervoneva and Paul S. Robinson and D. P. Beason and E. T. Carine and L. Soslowsky and R. Iozzo and D. Birk},
  journal={Journal of Cellular Biochemistry},
  year={2006},
  volume={98}
}
  • G. Zhang, Y. Ezura, +6 authors D. Birk
  • Published 2006
  • Medicine, Biology
  • Journal of Cellular Biochemistry
  • Tendon function involves the development of an organized hierarchy of collagen fibrils. Small leucine‐rich proteoglycans have been implicated in the regulation of fibrillogenesis and decorin is the prototypic member of this family. Decorin‐deficient mice demonstrate altered fibril structure and mechanical function in mature skin and tail tendons. However, the developmental role(s) of decorin needs to be elucidated. To define these role(s) during tendon development, tendons (flexor digitorum… CONTINUE READING
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