Decorin and suramin inhibit ocular fibroblast collagen production

  title={Decorin and suramin inhibit ocular fibroblast collagen production},
  author={Holger Mietz and Patricia Ch{\'e}vez-Barrios and M. W. Lieberman and Mark Wendt and Ronald L. Gross and Scott F. Basinger},
  journal={Graefe's Archive for Clinical and Experimental Ophthalmology},
• Background: The process of ocular wound healing with respect to glaucomatous filtering procedures is of current interest. Delaying this response in patients could possibly lead to more favorable surgical results. So far, only highly toxic antimetabolites have come into frequent clinical use. The possible efficacy of other groups of substances such as growth factor inhibitors has not yet been examined in vitro. • Methods: We exposed Tenon's capsule fibroblasts in tissue culture to various… CONTINUE READING