• Biology, Medicine
• Published in Cell cycle 2012
• DOI:10.4161/cc.11.2.19022

Deconvoluting mTOR biology.

@article{Weber2012DeconvolutingMB,
  title={Deconvoluting mTOR biology.},
  author={Jason D. Weber and David H. Gutmann},
  journal={Cell cycle},
  year={2012},
  volume={11 2},
  pages={
          236-48
        }
}

• Jason D. Weber, David H. Gutmann

In metazoans, TOR is an essential protein that functions as a master regulator of cellular growth and proliferation. Over the past decade, there has been an explosion of information about this critical master kinase, ranging from the composition of the TOR protein complex to its ability to act as an integrator of numerous extracellular signals. Unfortunately, this plethora of information has also raised numerous questions regarding TOR function. Currently, the prevailing view is that mammalian… CONTINUE READING

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