Deconstructing host-pathogen interactions in Drosophila

@inproceedings{Bier2012DeconstructingHI,
  title={Deconstructing host-pathogen interactions in Drosophila},
  author={Ethan Bier and Annabel Guichard},
  booktitle={Disease models & mechanisms},
  year={2012}
}
Many of the cellular mechanisms underlying host responses to pathogens have been well conserved during evolution. As a result, Drosophila can be used to deconstruct many of the key events in host-pathogen interactions by using a wealth of well-developed molecular and genetic tools. In this review, we aim to emphasize the great leverage provided by the suite of genomic and classical genetic approaches available in flies for decoding details of host-pathogen interactions; these findings can then… CONTINUE READING
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