Corpus ID: 199480498

Deconstructing Retinal Organoids: Single Cell RNA-Seq Reveals the Cellular Components of Human Pluripotent Stem Cell-Derived Retina

@inproceedings{oseph2019DeconstructingRO,
  title={Deconstructing Retinal Organoids: Single Cell RNA-Seq Reveals the Cellular Components of Human Pluripotent Stem Cell-Derived Retina},
  author={oseph and ollin and Achel and UEEN and IRTHE and ORGAU and Onathan and OXHEAD and Imon and OCKELL},
  year={2019}
}
  • oseph, ollin, +7 authors OCKELL
  • Published 2019
  • The rapid improvements in single cell sequencing technologies and analyses afford greater scope for dissecting organoid cultures composed of multiple cell types and create an opportunity to interrogate these models to understand tissue biology, cellular behavior and interactions. To this end, retinal organoids generated from human embryonic stem cells (hESCs) were analyzed by single cell RNA-sequencing (scRNA-Seq) at 3 time points of differentiation. Combinatorial data from all time points… CONTINUE READING
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