Decongestion strategies and renin-angiotensin-aldosterone system activation in acute heart failure.

@article{Mentz2015DecongestionSA,
  title={Decongestion strategies and renin-angiotensin-aldosterone system activation in acute heart failure.},
  author={Robert J. Mentz and Susanna R. Stevens and Adam D DeVore and Anuradha Lala and Justin M. Vader and Omar F Abouezzeddine and Prateeti P Khazanie and Margaret M. Redfield and Lynne Warner Stevenson and Christopher M. O'Connor and Steven Goldsmith and Bradley Bart and Kevin J. Anstrom and Adrian F. Hernandez and Eugene Braunwald and Gary Michael Felker},
  journal={JACC. Heart failure},
  year={2015},
  volume={3 2},
  pages={97-107}
}
OBJECTIVES The purpose of this study was to assess the relationship between biomarkers of renin-angiotensin-aldosterone system (RAAS) activation and decongestion strategies, worsening renal function, and clinical outcomes. BACKGROUND High-dose diuretic therapy in patients with acute heart failure (AHF) is thought to activate the RAAS; and alternative decongestion strategies, such as ultrafiltration (UF), have been proposed to mitigate this RAAS activation. METHODS This study analyzed 427… CONTINUE READING