Decompartmentalizing target validation—thinking outside the pipeline boxes

Abstract

Our appreciation of the timing and importance of target validation in the drug discovery process is under constant revision. Originally viewed as a “hit and run” event that merely triggers motivation to initiate screening for drug candidates, today’s view is that target validation is an ongoing process that permeates all phases of the drug discovery… (More)
DOI: 10.1007/s00109-006-0080-2

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