Decoding of cytosolic calcium oscillations in the mitochondria

@article{Hajnczky1995DecodingOC,
  title={Decoding of cytosolic calcium oscillations in the mitochondria},
  author={Gy{\"o}rgy Hajn{\'o}czky and Lawrence D. Robb-Gaspers and Michele B Seitz and A. P. Thomas},
  journal={Cell},
  year={1995},
  volume={82},
  pages={415-424}
}
Frequency-modulated oscillations of cytosolic Ca2+ ([Ca2+]c) are believed to be important in signal transduction, but it has been difficult to correlate [Ca2+]c oscillations directly with the activity of Ca(2+)-regulated targets. We have studied the control of Ca(2+)-sensitive mitochondrial dehydrogenases (CSMDHs) by monitoring mitochondrial Ca2+ ([Ca2+]m) and the redox state of flavoproteins and pyridine nucleotides simultaneously with [Ca2+]c in single hepatocytes. Oscillations of [Ca2+]c… CONTINUE READING
Highly Influential
This paper has highly influenced 29 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
350 Citations
26 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 350 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 26 references

Mitochondria in smooth muscle sequester

  • T.C.H. Mix, Drummond, M R., R. A. Tuft, F. S. Fay
  • 1994
1 Excerpt

Similar Papers

Loading similar papers…