Decoding cytosolic Ca2+ oscillations.

@article{Parekh2011DecodingCC,
  title={Decoding cytosolic Ca2+ oscillations.},
  author={A. Parekh},
  journal={Trends in biochemical sciences},
  year={2011},
  volume={36 2},
  pages={
          78-87
        }
}
  • A. Parekh
  • Published 2011
  • Biology, Medicine
  • Trends in biochemical sciences
  • A rise in cytosolic Ca(2+) concentration is used as a universal signalling mechanism to control biological processes as diverse as exocytosis, contraction, cell growth and cell death. Ca(2+) signals are often presented to cells in the form of Ca(2+) oscillations, with signalling information encoded in both amplitude and frequency of the Ca(2+) spikes. Recent studies have revealed that the sub-cellular spatial profile of the Ca(2+) oscillation is also important in activating cellular responses… CONTINUE READING
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    References

    SHOWING 1-10 OF 96 REFERENCES
    STIM Is a Ca2+ Sensor Essential for Ca2+-Store-Depletion-Triggered Ca2+ Influx
    • 1,805
    Store-operated calcium channels.
    • 2,206
    • PDF
    Ca2+ microdomains near plasma membrane Ca2+ channels: impact on cell function
    • A. Parekh
    • Biology, Medicine
    • The Journal of physiology
    • 2008
    • 195
    Mitochondrial control of calcium-channel gating: a mechanism for sustained signaling and transcriptional activation in T lymphocytes.
    • 259
    • PDF
    Spatial and temporal aspects of cellular calcium signaling
    • 475