Decoding critical long non-coding RNA in ovarian cancer epithelial-to-mesenchymal transition

@inproceedings{Mitra2017DecodingCL,
  title={Decoding critical long non-coding RNA in ovarian cancer epithelial-to-mesenchymal transition},
  author={Ramkrishna Mitra and Xi Chen and Evan J Greenawalt and Ujjwal Maulik and Wei Jiang and Zhongming Zhao and Christine M. Eischen},
  booktitle={Nature Communications},
  year={2017}
}
Long non-coding RNA (lncRNA) are emerging as contributors to malignancies. Little is understood about the contribution of lncRNA to epithelial-to-mesenchymal transition (EMT), which correlates with metastasis. Ovarian cancer is usually diagnosed after metastasis. Here we report an integrated analysis of >700 ovarian cancer molecular profiles, including genomic data sets, from four patient cohorts identifying lncRNA DNM3OS, MEG3, and MIAT overexpression and their reproducible gene regulation in… CONTINUE READING
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