Declining incidence of hepatocellular carcinoma in Osaka, Japan, from 1990 to 2003.

  title={Declining incidence of hepatocellular carcinoma in Osaka, Japan, from 1990 to 2003.},
  author={Hideo Tanaka and Yasuharu Imai and Naoki Hiramatsu and Yuri Ito and Kazuho Imanaka and Masahide Oshita and Taizo Hijioka and Kazuhiro Katayama and Iwao Yabuuchi and Harumasa Yoshihara and Atsuo Inoue and Michio Kato and Tetsuo Takehara and Shinji Tamura and Akinori Kasahara and Norio Hayashi and Hideaki Tsukuma},
  journal={Annals of internal medicine},
  volume={148 11},
Context Hepatitis C virus (HCV) infection in Japan began to spread during the 1920s, increased after World War II with an explosion in parenteral amphetamine use and paid blood donation, and decreased in the 1950s to 1960s with voluntary blood donation and penalties against amphetamine use. Evidence linking the trends in HCV infection to hepatocellular carcinoma rates in Japan is limited. Contribution Data from the Osaka Cancer Registry and 10 Osaka hospitals suggest that hepatocellular… CONTINUE READING


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