Declining asexual reproduction is suggestive of senescence in hydra: Comment on Martinez, D., “Mortality patterns suggest lack of senescence in hydra.” Exp Gerontol 33, 217–25

@article{Estep2010DecliningAR,
  title={Declining asexual reproduction is suggestive of senescence in hydra: Comment on Martinez, D., “Mortality patterns suggest lack of senescence in hydra.” Exp Gerontol 33, 217–25},
  author={Preston W. Estep},
  journal={Experimental Gerontology},
  year={2010},
  volume={45},
  pages={645-646}
}
  • Preston W. Estep
  • Published 1 September 2010
  • Medicine, Biology
  • Experimental Gerontology
A 1998 publication in Experimental Gerontology has become widely cited as providing experimental support for the existence of non-senescing organisms (Martinez, 1998). Fig. 1 in that publication shows thatHydra vulgaris does indeed have low age-specific mortality for an animal of its size. However, as the author notes, declining reproduction is sometimes another sign of senescence and asexual reproduction (budding) was a primary focus of that study. The Abstract reports the following: “The… Expand
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References

SHOWING 1-10 OF 11 REFERENCES
Mortality Patterns Suggest Lack of Senescence in Hydra
TLDR
To test for the presence or absence of aging in hydra, mortality and reproductive rates for three hydra cohorts have been analyzed for a period of four years and the results provide no evidence for aging. Expand
In Brief
TLDR
It is concluded that the two supposedly identical cells produced during cell division are functionally asymmetric; the old pole cell should be considered an aging parent repeatedly producing rejuvenated offspring and therefore immortality may be either too costly or mechanistically impossible in natural organisms. Expand
Senescent sperm performance in old male birds
TLDR
Evidence of declining sperm performance for important reproductive variables not only with age, but also with the sperm of old males performing differentially better in female medium than young males. Expand
The Functional Ecology of Clonal Animals
With the recent publication of two major symposia on their population and evolutionary biology (Jackson, Buss & Cook, 1985; Harper, Rosen & White, 1986), the tide of interest in the functional… Expand
Replicative ageing in the fission yeast Schizosaccharomyces pombe
TLDR
These experiments provide the first evidence of age asymmetry in cell fission and are consistent with the hypothesis of Jazwinski, that asymmetric division underlies culture immortality. Expand
Cell Movements in Hydra
TLDR
It appears that interstitial cells and nematoblasts move in bulk through the intercellular spaces in some situations, probably due to epithelial cell activities and is used to redistribute cells located in the interstitial spaces. Expand
Senescence in a Bacterium with Asymmetric Division
TLDR
This work presents evidence for senescence, a deterioration of function with age manifested as a drop in survival and reproduction in organisms that should be potentially immortal. Expand
Reproduction by Fragmentation in Corals
TLDR
It is concluded that a number of the most successful corals are adapted to fragment, and have incorporated fragmentation into their life histories. Expand
Effects of male age on the frequencies of germinal and heritable chromosomal abnormalities in humans and rodents.
TLDR
The weight of evidence suggests that the increasing trend toward fathering at older ages may have significant effects on the viability and genetic health of human pregnancies and offspring, primarily as a result of structural chromosomal aberrations in sperm. Expand
Advancing Paternal Age Is Associated with Deficits in Social and Exploratory Behaviors in the Offspring: A Mouse Model
TLDR
This study provides the strongest evidence for deleterious effects of advancing paternal age on social and exploratory behavior and de-novo chromosomal changes and/or inherited epigenetic changes are the most plausible explanatory factors. Expand
...
1
2
...