Declining asexual reproduction is suggestive of senescence in hydra: Comment on Martinez, D., “Mortality patterns suggest lack of senescence in hydra.” Exp Gerontol 33, 217–25

@article{Estep2010DecliningAR,
  title={Declining asexual reproduction is suggestive of senescence in hydra: Comment on Martinez, D., “Mortality patterns suggest lack of senescence in hydra.” Exp Gerontol 33, 217–25},
  author={Preston W. Estep},
  journal={Experimental Gerontology},
  year={2010},
  volume={45},
  pages={645-646}
}
  • Preston W. Estep
  • Published 1 September 2010
  • Environmental Science
  • Experimental Gerontology
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References

SHOWING 1-10 OF 11 REFERENCES

Mortality Patterns Suggest Lack of Senescence in Hydra

  • D. Martinez
  • Environmental Science
    Experimental Gerontology
  • 1998

In Brief

It is concluded that the two supposedly identical cells produced during cell division are functionally asymmetric; the old pole cell should be considered an aging parent repeatedly producing rejuvenated offspring and therefore immortality may be either too costly or mechanistically impossible in natural organisms.

Senescent sperm performance in old male birds

Evidence of declining sperm performance for important reproductive variables not only with age, but also with the sperm of old males performing differentially better in female medium than young males.

The Functional Ecology of Clonal Animals

With the recent publication of two major symposia on their population and evolutionary biology (Jackson, Buss & Cook, 1985; Harper, Rosen & White, 1986), the tide of interest in the functional…

Replicative ageing in the fission yeast Schizosaccharomyces pombe

These experiments provide the first evidence of age asymmetry in cell fission and are consistent with the hypothesis of Jazwinski, that asymmetric division underlies culture immortality.

Cell Movements in Hydra

It appears that interstitial cells and nematoblasts move in bulk through the intercellular spaces in some situations, probably due to epithelial cell activities and is used to redistribute cells located in the interstitial spaces.

Senescence in a Bacterium with Asymmetric Division

This work presents evidence for senescence, a deterioration of function with age manifested as a drop in survival and reproduction in organisms that should be potentially immortal.

Reproduction by Fragmentation in Corals

It is concluded that a number of the most successful corals are adapted to fragment, and have incorporated fragmentation into their life histories.

Effects of male age on the frequencies of germinal and heritable chromosomal abnormalities in humans and rodents.

Advancing Paternal Age Is Associated with Deficits in Social and Exploratory Behaviors in the Offspring: A Mouse Model

This study provides the strongest evidence for deleterious effects of advancing paternal age on social and exploratory behavior and de-novo chromosomal changes and/or inherited epigenetic changes are the most plausible explanatory factors.