Decline in the Prevalence of Antibodies to Herpes Simplex Virus Types 1 and 2 Among Israeli Young Adults Between 1984 and 2002

@article{Davidovici2006DeclineIT,
  title={Decline in the Prevalence of Antibodies to Herpes Simplex Virus Types 1 and 2 Among Israeli Young Adults Between 1984 and 2002},
  author={Batya Davidovici and Itamar Grotto and Ran D. Balicer and Noah Jamie Robinson and Dani Cohen},
  journal={Sexually Transmitted Diseases},
  year={2006},
  volume={33},
  pages={641-645}
}
Objective: The objective of this study was to estimate the seroprevalence of herpes simplex virus (HSV) types 1 and 2 in male and female soldiers discharged from the Israel Defense Force (IDF) over a period of 18 years. Goal: The goal of this study was to study the secular trends of HSV-1 and HSV-2 infection rates in Israeli young adults. Study Design: Three consecutive cross-sectional studies were carried out on stored sera of systematic random samples of soldiers (median age = 20.8… 
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The seroprevalence of HSV-2 in pregnant women appears to have decreased in Sweden during the past decade, which may reflect changes in sexual behaviour.
Decreasing seroprevalence of herpes simplex virus type 1 and type 2 in Germany leaves many people susceptible to genital infection: time to raise awareness and enhance control
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The reduced seroprevalences of HSV1 and HSV2 leave more people susceptible to genital HSV 1/2 infections, and educational interventions should especially target pregnant women, their partners, and people at risk of HIV.
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HSV-1 epidemiology is transitioning away from its historical pattern of oral acquisition in childhood, and every year, seroprevalence is declining by 1% and the proportion of HSV- 1 in genital herpes is increasing by 1%.
Hemophagocytic lymphohistiocytosis due to acute primary herpes simplex virus 1 infection.

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