Decline in the Prevalence of Antibodies to Herpes Simplex Virus Types 1 and 2 Among Israeli Young Adults Between 1984 and 2002

  title={Decline in the Prevalence of Antibodies to Herpes Simplex Virus Types 1 and 2 Among Israeli Young Adults Between 1984 and 2002},
  author={Batya Davidovici and Itamar Grotto and Ran D. Balicer and Noah Jamie Robinson and Dani Cohen},
  journal={Sexually Transmitted Diseases},
Objective: The objective of this study was to estimate the seroprevalence of herpes simplex virus (HSV) types 1 and 2 in male and female soldiers discharged from the Israel Defense Force (IDF) over a period of 18 years. Goal: The goal of this study was to study the secular trends of HSV-1 and HSV-2 infection rates in Israeli young adults. Study Design: Three consecutive cross-sectional studies were carried out on stored sera of systematic random samples of soldiers (median age = 20.8… 
Decreasing prevalence of herpes simplex virus-2 antibodies in selected groups of women in Sweden.
The seroprevalence of HSV-2 in pregnant women appears to have decreased in Sweden during the past decade, which may reflect changes in sexual behaviour.
Decreasing seroprevalence of herpes simplex virus type 1 and type 2 in Germany leaves many people susceptible to genital infection: time to raise awareness and enhance control
The reduced seroprevalences of HSV1 and HSV2 leave more people susceptible to genital HSV 1/2 infections, and educational interventions should especially target pregnant women, their partners, and people at risk of HIV.
Neonatal Herpes Simplex Virus Infections in Israel
The incidence of NHSV infection in Israel was found to be similar to the lower part of the scale reported in the United States, however higher than the incidence reported in Canada or in Europe.
Herpes simplex virus type 1 in Europe: systematic review, meta-analyses and meta-regressions
HSV-1 epidemiology is transitioning away from its historical pattern of oral acquisition in childhood, and every year, seroprevalence is declining by 1% and the proportion of HSV- 1 in genital herpes is increasing by 1%.
Hemophagocytic lymphohistiocytosis due to acute primary herpes simplex virus 1 infection.


A sero-epidemiological study of herpes virus type 1 and 2 infection in Israel.
  • M. Isacsohn, Z. Smetana, A. Morag
  • Medicine, Biology
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology
  • 2002
Seroprevalence of herpes simplex virus type 1 and type 2 in selected German populations—relevance for the incidence of genital herpes
Although the rate of infections with HSV‐2 is relatively low in the German population, attention should be given to the further development in adolescents, especially in view of a possible decrease ofHSV‐1 seroprevalence in childhood.
A seroprevalence study of herpes virus type 2 infection in Israeli women: implications for routine screening.
The data support the conclusion that there is no justification for routine prenatal HSV-2 screening in Israel in a healthy female population.
Herpes Simplex Virus Type 2 in the United States, 1976 to 1994
The seroprevalence of HSV-2 in persons 12 years of age or older in the United States was 21.9 percent (95 percent confidence interval, 20.2 to 23.6 percent), corresponding to 45 million infected people in the noninstitutionalized civilian population.
New Estimates of Herpes Simplex Virus Type 2 Seroprevalence in England: ‘High’ But Stable Seroprevalence Over the Last Decade
There was no evidence of a change in seroprevalence in HSV-2 infection in England between 1991 and 2000 after adjustment for age, sex, and geographic location.
Prevalence of Antibodies to Herpes Simplex Virus in Pregnant Women in Stockholm in 1969, 1983 and 1989: Implications for STD Epidemiology
Prevalence of antibody to herpes simplex virus types 1 and 2 was assessed in consecutive serum samples from a total of 3700 women pregnant in 1969, 1983, or 1989, and cannot be taken as direct evidence of increased rate of partner change during this 20-year period.
Decline of herpes simplex virus type 2 and Chlamydia trachomatis infections from 1970 to 1993 indicated by a similar change in antibody pattern.
High antibody rates against both HSV-2 and Ct in older pregnant women in the early 1990s may reflect a high incidence of these infections around 1970, and declining rates of antibodies in the youngest women would suggest a declining incidence of primary infections in this group.
The burden of infection with HSV-1 and HSV-2 in England and Wales: implications for the changing epidemiology of genital herpes
The incidence of HSV-1 infection in childhood is falling in England and Wales, and the rate of infection is significantly lower than that described for the general population in the United States and developing countries.
Strong decline in herpes simplex virus antibodies over time among young homosexual men is associated with changing sexual behavior.
The authors conclude that among young homosexual men in this study, the strong decrease in HSV seroprevalence was associated with a concurrent shift in sexual behavior, and these data suggest an increasing sexual component inHSV1 transmission over time.