Decline in Prevalence of Neural Tube Defects in a High-Risk Region of the United States

@article{Stevenson2000DeclineIP,
  title={Decline in Prevalence of Neural Tube Defects in a High-Risk Region of the United States},
  author={Roger E. Stevenson and William P. Allen and Gurpur Shashidhar Pai and Robert Best and Laurie H. Seaver and Jane H. Dean and Shirley J. Thompson},
  journal={Pediatrics},
  year={2000},
  volume={106},
  pages={677 - 683}
}
Objectives. To conduct surveillance for neural tube defects (NTDs) in a high-risk region of the United States and to prevent occurrence and recurrence of NTDs through the periconceptional use of folic acid supplements. Design. Active and passive methods were used for surveillance of NTD-affected pregnancies and births during a 6-year period (October 1992–September 1998). Individual genetic counseling was used to prevent NTD recurrences and a public awareness campaign was used to reduce NTD… 

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