Decision tree–driven tandem mass spectrometry for shotgun proteomics

@article{Swaney2008DecisionTT,
  title={Decision tree–driven tandem mass spectrometry for shotgun proteomics},
  author={Danielle L. Swaney and G Mcalister and Joshua J. Coon},
  journal={Nature Methods},
  year={2008},
  volume={5},
  pages={959-964}
}
Mass spectrometry has become a key technology for modern large-scale protein sequencing. Tandem mass spectrometry, the process of peptide ion dissociation followed by mass-to-charge ratio (m/z) analysis, is the critical component for peptide identification. Recent advances in mass spectrometry now permit two discrete, and complementary, types of peptide ion fragmentation: collision-activated dissociation (CAD) and electron transfer dissociation (ETD) on a single instrument. To exploit this… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 114 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 30 references

Large-scale phosphorylation analysis of mouse liver.

Proceedings of the National Academy of Sciences of the United States of America • 2007

Similar Papers

Loading similar papers…