Decision for Retransplantation of the Liver: An Experience- and Cost-Based Analysis

@article{Azoulay2002DecisionFR,
  title={Decision for Retransplantation of the Liver: An Experience- and Cost-Based Analysis},
  author={D. Azoulay and M. M. Linhares and E. Huguet and V. Delvart and D. Castaing and R. Adam and P. Ichai and F. Saliba and A. Lemoine and D. Samuel and H. Bismuth},
  journal={Annals of Surgery},
  year={2002},
  volume={236},
  pages={713-721}
}
ObjectiveTo determine the patient factors affecting patient outcome of first liver retransplantation at a single center to help in the decision process for retransplantation. Summary Background DataGiven the critical organ shortage, one of the most controversial questions is whether hepatic retransplantation, the only chance of survival for patients with a failing first organ, should be offered liberally despite its greater cost, worse survival, and the inevitable denial of access to primary… Expand
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Hematic retransplantation, although life-saving in almost 50% of patients with a failing liver allograft, is costly and uses scarce donor organs inefficiently and should assist in the rational application of retransplplantation. Expand
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Preoperatively older age, high United Network of Organ Sharing score, inpatient status, elevated bilirubin, and creatinine levels were associated with increased mortality after a second transplant, and these factors assist in the stratification of patients awaiting retransplantation. Expand
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It is demonstrated that the Cox proportional hazards regression system can be employed to identify a subgroup of patients in which the expected outcome is too poor to justify retransplantation, and may assist in the rational selection of patients suitable for retransplplantation. Expand
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