Decision Making at a Subcellular Level Determines the Outcome of Bacteriophage Infection

Abstract

When the process of cell-fate determination is examined at single-cell resolution, it is often observed that individual cells undergo different fates even when subject to identical conditions. This "noisy" phenotype is usually attributed to the inherent stochasticity of chemical reactions in the cell. Here we demonstrate how the observed single-cell… (More)
DOI: 10.1016/j.cell.2010.03.034

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