Decision-Making Impairments in Patients with Parkinson’s Disease

  title={Decision-Making Impairments in Patients with Parkinson’s Disease},
  author={Matthias Brand and Kirsten Labudda and Elke Kalbe and R{\"u}diger Hilker and David Emmans and Gerd A. Fuchs and Josef Kessler and Hans Joachim Markowitsch},
  booktitle={Behavioural neurology},
A high percentage of Parkinson's disease (PD) patients show cognitive impairments in addition to the cardinal motor symptoms. These deficits primarily concern executive functions most probably linked to dysfunctions in prefrontal regions due to decreased dopaminergic transmission in fronto-striatal loops. To investigate possible associations between decision-making and executive functions in PD, we examined 20 non-demented PD patients and 20 healthy control subjects with a neuropsychological… CONTINUE READING


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