Decipinin A and decipienolides A and B: new bioactive metabolites from the coprophilous fungus Podospora decipiens.

Abstract

Decipinin A (1), a new compound with antifungal and antibacterial activity, has been isolated from liquid cultures of the coprophilous fungus Podospora decipiens (JS 270). Two new tetracyclic sesquiterpene lactones, decipienolides A (2) and B (3), were also obtained from this isolate as an inseparable mixture of epimers that showed antibacterial activity. The structures of 1-3 were elucidated by analysis of 1D and 2D NMR data, aided by chemical shift comparisons to related compounds.

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@article{Che2002DecipininAA, title={Decipinin A and decipienolides A and B: new bioactive metabolites from the coprophilous fungus Podospora decipiens.}, author={Yongsheng Che and James B Gloer and B. Koster and David Malloch}, journal={Journal of natural products}, year={2002}, volume={65 6}, pages={916-9} }