Deciphering the interplay between two independent functions of the small RNA regulator SgrS in Salmonella.

@article{Balasubramanian2013DecipheringTI,
  title={Deciphering the interplay between two independent functions of the small RNA regulator SgrS in Salmonella.},
  author={Divya Balasubramanian and Carin K. Vanderpool},
  journal={Journal of bacteriology},
  year={2013},
  volume={195 20},
  pages={4620-30}
}
Bacterial dual-function small RNAs regulate gene expression by RNA-RNA base pairing and also code for small proteins. SgrS is a dual-function small RNA in Escherichia coli and Salmonella that is expressed under stress conditions associated with accumulation of sugar-phosphates, and its activity is crucial for growth during stress. The base-pairing function of SgrS regulates a number of mRNA targets, resulting in reduced uptake and enhanced efflux of sugars. SgrS also encodes the SgrT protein… CONTINUE READING
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