Deciphering the human platelet sheddome.

Abstract

Activated platelets shed surface proteins, potentially modifying platelet function as well as providing a source of bioactive fragments. Previous studies have identified several constituents of the platelet sheddome, but the full extent of shedding is unknown. Here we have taken a global approach, analyzing protein fragments in the supernate of activated… (More)
DOI: 10.1182/blood-2010-05-283838

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