Deciphering the anti-angiogenic effect of endostatin/cyclophosphamide to normalize tumor micrangium through notch signaling pathway in colon cancer

@inproceedings{Lv2015DecipheringTA,
  title={Deciphering the anti-angiogenic effect of endostatin/cyclophosphamide to normalize tumor micrangium through notch signaling pathway in colon cancer},
  author={Jin-Yan Lv and Tai-Yuan Hu and Ruo-yu Wang and Jin-Ming Zhu and Gang Sam Wang},
  booktitle={World journal of surgical oncology},
  year={2015}
}
BACKGROUND The invasion of colon cancer is associated with the tumor angiogenesis. Endostatin is an important anti-angiogenic agent, and the additive effect of endostatin with a chemotherapeutic agent, cyclophosphamide, on micrangium has not been established. METHODS Male BALB/c strain nude mice were injected with human colorectal carcinoma cells (HCT-116… CONTINUE READING