Deciphering the 8q24.21 association for glioma.

@article{EncisoMora2013DecipheringT8,
  title={Deciphering the 8q24.21 association for glioma.},
  author={V. Enciso-Mora and F. Hosking and B. Kinnersley and Yufei Wang and S. Shete and D. Z{\'e}l{\'e}nika and P. Broderick and A. Idbaih and J. Delattre and K. Hoang‐Xuan and Y. Marie and A. D. Di Stefano and M. Labussi{\`e}re and Sara E Dobbins and B. Boisselier and P. Ciccarino and M. Rossetto and G. Armstrong and Yanhong Liu and K. Gousias and J. Schramm and C. Lau and S. Hepworth and K. Strauch and M. M{\"u}ller-Nurasyid and S. Schreiber and A. Franke and S. Moebus and L. Eisele and A. Forsti and K. Hemminki and I. Tomlinson and A. Swerdlow and M. Lathrop and M. Simon and M. Bondy and M. Sanson and R. Houlston},
  journal={Human molecular genetics},
  year={2013},
  volume={22 11},
  pages={
          2293-302
        }
}
We have previously identified tagSNPs at 8q24.21 influencing glioma risk. We have sought to fine-map the location of the functional basis of this association using data from four genome-wide association studies, comprising a total of 4147 glioma cases and 7435 controls. To improve marker density across the 700 kb region, we imputed genotypes using 1000 Genomes Project data and high-coverage sequencing data generated on 253 individuals. Analysis revealed an imputed low-frequency SNP rs55705857… Expand
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