Deciphering systemic lupus erythematosus-associated serum biomarkers reflecting apoptosis and disease activity.

@article{Delfani2017DecipheringSL,
  title={Deciphering systemic lupus erythematosus-associated serum biomarkers reflecting apoptosis and disease activity.},
  author={Payam Delfani and Gunnar K. Sturfelt and B Gullstrand and Anders Carlsson and M Kassandra and Carl A. K. Borrebaeck and Anders A. Bengtsson and Christer Wingren},
  journal={Lupus},
  year={2017},
  volume={26 4},
  pages={373-387}
}
Systemic lupus erythematosus (SLE) is a severe chronic inflammatory autoimmune connective tissue disease. Despite major efforts, SLE remains a poorly understood disease with unpredictable course, unknown etiology and complex pathogenesis. Apoptosis combined with deficiency in clearing apoptotic cells is an important etiopathogenic event in SLE, which could contribute to the increased load of potential autoantigen(s); however, the lack of disease-specific protein signatures deciphering SLE and… CONTINUE READING

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