Deciphering apicoplast targeting signals--feature extraction from nuclear-encoded precursors of Plasmodium falciparum apicoplast proteins.

@article{Zuegge2001DecipheringAT,
  title={Deciphering apicoplast targeting signals--feature extraction from nuclear-encoded precursors of Plasmodium falciparum apicoplast proteins.},
  author={Jochen Zuegge and Stuart H. Ralph and Michael Schmuker and Geoffrey Ian McFadden and Georg Schneider},
  journal={Gene},
  year={2001},
  volume={280 1-2},
  pages={
          19-26
        }
}
The malaria causing protozoan Plasmodium falciparum contains a vestigal, non-photosynthetic plastid, the apicoplast. Numerous proteins encoded by nuclear genes are targeted to the apicoplast courtesy of N-terminal extensions. With the impending sequence completion of an entire genome of the malaria parasite, it is important to have software tools in place for prediction of subcellular locations for all proteins. Apicoplast targeting signals are bipartite; containing a signal peptide and a… CONTINUE READING
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