Deciphering Multiplicity of HIV-1C Infection: Transmission of Closely Related Multiple Viral Lineages

@inproceedings{Novitsky2016DecipheringMO,
  title={Deciphering Multiplicity of HIV-1C Infection: Transmission of Closely Related Multiple Viral Lineages},
  author={Vlad Novitsky and Sikhulile Moyo and Rui Wang and Simani Gaseitsiwe and Myron E Essex},
  booktitle={PloS one},
  year={2016}
}
BACKGROUND A single viral variant is transmitted in the majority of HIV infections. However, about 20% of heterosexually transmitted HIV infections are caused by multiple viral variants. Detection of transmitted HIV variants is not trivial, as it involves analysis of multiple viral sequences representing intra-host HIV-1 quasispecies. METHODOLOGY We… CONTINUE READING