Deciphering Epithelial–Mesenchymal Transition Regulatory Networks in Cancer through Computational Approaches

@inproceedings{Burger2017DecipheringET,
  title={Deciphering Epithelial–Mesenchymal Transition Regulatory Networks in Cancer through Computational Approaches},
  author={Gerhard A. Burger and Erik H. J. Danen and Joost B. Beltman},
  booktitle={Front. Oncol.},
  year={2017}
}
Epithelial-mesenchymal transition (EMT), the process by which epithelial cells can convert into motile mesenchymal cells, plays an important role in development and wound healing but is also involved in cancer progression. It is increasingly recognized that EMT is a dynamic process involving multiple intermediate or "hybrid" phenotypes rather than an "all-or-none" process. However, the role of EMT in various cancer hallmarks, including metastasis, is debated. Given the complexity of EMT… CONTINUE READING
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