Decidual natural killer cell interactions with trophoblasts are impaired in pregnancies at increased risk of preeclampsia.

@article{Wallace2013DecidualNK,
  title={Decidual natural killer cell interactions with trophoblasts are impaired in pregnancies at increased risk of preeclampsia.},
  author={Alison E. Wallace and Amanda J Host and Guy Stj Whitley and Judith E. Cartwright},
  journal={The American journal of pathology},
  year={2013},
  volume={183 6},
  pages={1853-1861}
}
Transformation of the uterine spiral arteries (SAs) during pregnancy is critical to support the developing fetus, and is impaired in some pregnancy disorders, including preeclampsia. Decidual natural killer (dNK) cells play a role in SA remodeling, although their interactions with fetal trophoblast remain unclear. A uterine artery Doppler resistance index (RI) in the first trimester of pregnancy can be used as a proxy measure of the extent of SA remodeling; we have used this technique to… CONTINUE READING
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