Deceleration of age-specific mortality rates in chromosomal homozygotes and heterozygotes of Drosophila melanogaster.

@article{Fukui1996DecelerationOA,
  title={Deceleration of age-specific mortality rates in chromosomal homozygotes and heterozygotes of Drosophila melanogaster.},
  author={Hank H. Fukui and Lucy F. Ackert and James W. Curtsinger},
  journal={Experimental gerontology},
  year={1996},
  volume={31 4},
  pages={517-31}
}
Age-specific mortality trajectories were estimated in mixed-sex cohorts of D. melanogaster. We studied 22,000 flies that were either second-chromosome homozygotes or heterozygotes with a randomized genetic background. Broad-sense heritabilities for longevity were estimated to be 6% for males and 9% for females. Heterozygotes lived longer than homozygotes on average, but there were exceptions to the usual heterotic pattern; in several crosses parental homozygotes had average life spans as long… CONTINUE READING

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