Decanucleotide insertion polymorphism of F7 significantly influences the risk of thrombosis in patients with essential thrombocythemia.

@article{BuxhoferAusch2014DecanucleotideIP,
  title={Decanucleotide insertion polymorphism of F7 significantly influences the risk of thrombosis in patients with essential thrombocythemia.},
  author={Veronika Buxhofer-Ausch and Damla Olcaydu and Bettina Gisslinger and Martin Schalling and Sophie Frantal and Juergen Thiele and Leonhard M{\"u}llauer and Hans-Michael Kvasnicka and Herbert Hans Watzke and Robert Kralovics and Heinz Gisslinger},
  journal={European journal of haematology},
  year={2014},
  volume={93 2},
  pages={103-11}
}
OBJECTIVE There is strong evidence that certain thrombophilic single nucleotide polymorphisms (SNPs) account for an increased risk of thrombosis. The additive impact of inherited thrombotic risk factors to a certain disease- immanent thrombotic risk is vastly unknown. Therefore, we aimed to investigate the influence of three novel, preselected SNPs on the risk of thrombosis in patients diagnosed with myeloproliferative neoplasm (MPN). METHOD In 167 patients with a diagnosis of essential… CONTINUE READING