Debunking the pathophysiological puzzle of dystonia--with special reference to botulinum toxin therapy.

@article{Kaovsk2011DebunkingTP,
  title={Debunking the pathophysiological puzzle of dystonia--with special reference to botulinum toxin therapy.},
  author={Petr Kaňovsk{\'y} and RaymondL. Rosales},
  journal={Parkinsonism & related disorders},
  year={2011},
  volume={17 Suppl 1},
  pages={
          S11-4
        }
}
New neurophysiological insights into the natural behaviour of dystonia, obtained during the successful botulinum toxin A (BoNT) treatment of the disorder, have urged the inclusion of sensory (and particularly somatosensory) mechanisms into the pathophysiological background of dystonia. Muscle spindles play a pivotal role in the generation of dystonic movements. Abnormal behaviour in the muscle spindles that generates an irregular proprioceptive input via the group-IA afferents may result in… CONTINUE READING
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Task - speci fi c hand dystonia : can too much plasticity be bad for you ?

  • AJ Nelson, DT Blake, R Chen
  • Trends Neurosci
  • 2006

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