Debunking dogma: Surgery for four or more colorectal liver metastases is justified

@article{Pawlik2006DebunkingDS,
  title={Debunking dogma: Surgery for four or more colorectal liver metastases is justified},
  author={M.P.H. Timothy M. Pawlik and Eddie K. Abdalla and Lee M. Ellis and J. Nicholas Vauthey and Steven A. Curley},
  journal={Journal of Gastrointestinal Surgery},
  year={2006},
  volume={10},
  pages={240-248}
}
Treatment of four or more colorectal liver metastases (CRLMs) is controversial and remains a relative contraindication to surgery at some institutions. We sought to assess the outcome of patients with four or more CRLMs treated with surgery. Patients (159) with four or more CRLMs were treated surgically at a single institution. The median number of treated lesions was 5 (range, 4–14). The majority of patients received neoadjuvant chemotherapy (89.9%). Forty-six (29.0%) patients underwent… CONTINUE READING

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