Deaths Resulting From Hypocalcemia After Administration of Edetate Disodium: 2003-2005
@article{Brown2006DeathsRF, title={Deaths Resulting From Hypocalcemia After Administration of Edetate Disodium: 2003-2005}, author={M. Brown and T. Willis and B. Omalu and Richard D. Leiker}, journal={Pediatrics}, year={2006}, volume={118}, pages={e534 - e536} }
From 2003 to 2005, deaths of 3 individuals as a result of cardiac arrest caused by hypocalcemia during chelation therapy were reported to the Centers for Disease Control and Prevention. Two were children, both of whom were treated with edetate disodium. At the time of this writing, the adult case was still under investigation. No previous cases of death resulting from hypocalcemia during chelation have been reported. From our experience and review of the literature, we suggest that health care… CONTINUE READING
Topics from this paper
Paper Mentions
Blog Post
89 Citations
EDTA chelation reappraisal following new clinical trials and regular use in millions of patients: review of preliminary findings and risk/benefit assessment
- Medicine
- Toxicology mechanisms and methods
- 2013
- 23
Magnesium Therapy in a Hypocalcemic African Grey Parrot (Psittacus erithacus)
- Biology, Medicine
- Journal of avian medicine and surgery
- 2012
- 10
Commentary on the Abuse of Metal Chelation Therapy in Patients with Autism Spectrum Disorders
- Medicine
- Journal of Medical Toxicology
- 2013
- 12
Advances in the prevention and management of central-line-associated bloodstream infections: The role of chelator-based catheter locks.
- Medicine
- Infection control and hospital epidemiology
- 2019
- 1
Guidance for Clinical Treatment of Metal Poisonings—Use and Misuse of Chelating Agents
- Chemistry
- 2016
- 9
ACMT Recommends Against Use of Post-Chelator Challenge Urinary Metal Testing
- Medicine
- Journal of Medical Toxicology
- 2017
- 1
References
SHOWING 1-10 OF 18 REFERENCES
The use of chelating agents in the treatment of acute and chronic lead intoxication in childhood.
- Medicine
- The Journal of pediatrics
- 1968
- 211
Fatal pediatric lead poisoning--New Hamphshire, 2000.
- Medicine
- MMWR. Morbidity and mortality weekly report
- 2001
- 26
Preventing lead poisoning in young children. A statement by the Center for Disease Control.
- Medicine
- The Journal of pediatrics
- 1978
- 158
- PDF
Preventing lead poisoning in young children: A statement by the Centers for Disease Control, October 1991
- Medicine
- 1991
- 434
meso-2,3-Dimercaptosuccinic acid: chemical, pharmacological and toxicological properties of an orally effective metal chelating agent.
- Medicine
- Annual review of pharmacology and toxicology
- 1990
- 81
Lead, zinc and copper decorporation during calcium disodium ethylenediamine tetraacetate treatment of lead-poisoned children.
- Chemistry, Medicine
- The Journal of pharmacology and experimental therapeutics
- 1986
- 37
Blood lead levels--United States, 1999-2002.
- Medicine
- MMWR. Morbidity and mortality weekly report
- 2005
- 79
- PDF
Deaths related to lead poisoning in the United States, 1979-1998.
- Medicine
- Environmental research
- 2003
- 38