Death ligands and granulysin: mechanisms of tumor cell death induction and therapeutic opportunities.

Abstract

The immune system plays a key role in cancer immune surveillance to control tumor development. The final goal is recognizing and killing transformed cells and consequently the elimination of the tumor. The main effector cell types exerting cytotoxicity against tumors are natural killer (NK) cells and cytotoxic T lymphocytes (CTLs). Although the mechanism of… (More)
DOI: 10.2217/imt.15.56

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