Dead space loading and exercise limitation in patients with interstitial lung disease.

@article{Marciniuk1994DeadSL,
  title={Dead space loading and exercise limitation in patients with interstitial lung disease.},
  author={Darcy D. Marciniuk and Richard W. E. Watts and Charles G. Gallagher},
  journal={Chest},
  year={1994},
  volume={105 1},
  pages={183-9}
}
STUDY DESIGN We tested the hypothesis that maximal exercise performance in subjects with interstitial lung disease (ILD) is limited by respiratory factors. Assuming this is so, ventilatory stimulation by added dead space (VD) should impair exercise capacity. METHODS Six subjects with ILD each underwent three maximal incremental exercise studies on a bicycle ergometer; control 1, added VD, and control 2. During the VD study, external VD (500 ml) was added to the circuit, and results obtained… CONTINUE READING
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