Deacetylation of p53 induces autophagy by suppressing Bmf expression

@inproceedings{Contreras2013DeacetylationOP,
  title={Deacetylation of p53 induces autophagy by suppressing Bmf expression},
  author={Amelia U. Contreras and Yohannes A. Mebratu and M C Gamero Delgado and Gilbert Montano and Chien-an A. Hu and Stefan W Ryter and Augustine M. K. Choi and Yuting Lin and Jialing Xiang and Hitendra S Chand and Yohannes Tesfaigzi},
  booktitle={The Journal of cell biology},
  year={2013}
}
Interferon γ (IFN-γ)-induced cell death is mediated by the BH3-only domain protein, Bik, in a p53-independent manner. However, the effect of IFN-γ on p53 and how this affects autophagy have not been reported. The present study demonstrates that IFN-γ down-regulated expression of the BH3 domain-only protein, Bmf, in human and mouse airway epithelial cells in a p53-dependent manner. p53 also suppressed Bmf expression in response to other cell death-stimulating agents, including ultraviolet… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 21 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 58 REFERENCES

Similar Papers

Loading similar papers…