DeFries-Fulker analysis of twin data with skewed distributions: cautions and recommendations from a study of children's use of verb inflections.

@article{Bishop2005DeFriesFulkerAO,
  title={DeFries-Fulker analysis of twin data with skewed distributions: cautions and recommendations from a study of children's use of verb inflections.},
  author={Dorothy V. M. Bishop},
  journal={Behavior genetics},
  year={2005},
  volume={35 4},
  pages={479-90}
}
DeFries-Fulker (DF) analysis is an adaptation of multiple regression that is used to estimate heritability of extreme scores (h(g)2) on a dimension. Probands are identified as scoring below a cutoff that defines impairment, and one then uses regression to predict the scores of co-twins from the proband scores and a term that denotes the genetic relationship between twins (1.0 for MZ and 0.5 for DZ twins). This paper reports illustrative data and simulations for the situation where the… CONTINUE READING
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