De novo synthesis of N and P proteins as a key step in Sendai virus gene expression.

@article{Wiegand2007DeNS,
  title={De novo synthesis of N and P proteins as a key step in Sendai virus gene expression.},
  author={Marian Alexander Wiegand and Sascha Bossow and Sabine Schlecht and W. J. Neubert},
  journal={Journal of virology},
  year={2007},
  volume={81 24},
  pages={
          13835-44
        }
}
Among the members of the paramyxovirus family, the transcription process and the components involved have been studied under in vitro conditions thus far. Here, we reexamined the function of the viral RNA-dependent RNA polymerase through infection studies with Sendai virus (SeV) N and P deletion (Delta) mutants. To elucidate solely transcription-specific processes, all virus mutants also were rendered deficient in genome replication. Using mutant SeV DeltaP, the earlier suspected supplemental… CONTINUE READING

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