De novo sequencing of plant genomes using second-generation technologies

@article{Imelfort2009DeNS,
  title={De novo sequencing of plant genomes using second-generation technologies},
  author={Michael Imelfort and David Edwards},
  journal={Briefings in bioinformatics},
  year={2009},
  volume={10 6},
  pages={609-18}
}
The ability to sequence the DNA of an organism has become one of the most important tools in modern biological research. Until recently, the sequencing of even small model genomes required substantial funds and international collaboration. The development of 'second-generation' sequencing technology has increased the throughput and reduced the cost of sequence generation by several orders of magnitude. These new methods produce vast numbers of relatively short reads, usually at the expense of… CONTINUE READING